The Bios Life company - Unicity, is proud to share another amazing formulation to eradicate heart disease - naturally. Science Brief Omega-3 fatty acids are n-3 polyunsaturated fatty acids (n3-PUFA). Eicosapentaenoic acid (EPA) and Docahexanoic acid (DHA) are the two primary components of omega 3 fatty acids from fish. Diets high in theses oil have been long recognized as beneficial for heart disease. While Statins have been shown very effective for lowering LDL cholesterol, even with maximal doses CV risk is only decreased 30%.1 To provide maximal patient benefit, multiple risk markers, in addition to LDL, must be addressed. Fish oils have been shown to be helpful by increasing HDL and decreasing triglycerides.2 At doses of 2–4 grams per day, Omega-3’s can Reduce TG levels by 30% - 35% 3 *An increased TG level has been found to be an independent risk factor for CVD. 4 Promote a shift of LDL-C to larger, less dense (healthier) particles, 5,6 Raise HDL-Cholesterol, 3 Inhibit platelet aggregation, and Reduce ventricular arrhythmias. 7 Omega-3’s are generally well tolerated and compatible with statins and other therapies. The typical American Diet is estimated to include only 100 -200 mg per day of DHA and EPA. 1 Only high fish intake of the particularly oily fish (mackerel, herring, and salmon) will provide the recommended 2–4 grams per day. In 2003 the US environmental Protection Agency issued warnings about pollutants in fish and fish oil such as mercury, dioxin, DDT, and other chemicals. 9 Since many are recommending doses above 3,000 mg /day for cardiovascular risk reduction, purified forms of EPA and DHA are essential. . . Here's to Eradicating Heart Disease - Naturally References 1 Impact of lipid treatment in cardiovascular risk reduction: new therapeutic targets. Eur Heart J 2005; Supplement L-16- L20 2 Diets and cardiovascular disease: an evidence based assessment. J Am Coll Cardiol 2005;45:1379-1387 3 N-3 fatty acids and lipoproteins: comparison of results from human and animal studies. Lipids. 1996;31:243-252 4 Plasma triglyceride level is a risk factor for cardiovascular disease independent of high density lipoprotein cholesterol level: a meta-analysis of population based prospective studies. J Cariovasc Risk 1996;3:213-219 5 Current perspectives on the management of hypertriglyceridemia. Am Heart J. 2000;140:232-240 6 Pharmacologic management of Hyperlipidemia, Br J Diabetes Vasc Dis. 2003;3:204-210 7 Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils. Circulation. 2003;102:26462652 8 Polyunsaturated fatty acids in the food chain in the United States, Am J Clin Nutr. 2000;71(1 suppl): 179S-188S 9 US Food and Drug Administration. US Environmental Protection Agency. What You Need to Know About Mercury in Fish and Shellfish. March 2004. EPA 823-F-04-009

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